Pharmaceuticals

by admin admin No Comments

Hope of Good Health: Pharma-Nutrition

Pharma-Nutrition as a subject by itself, considering one is not complete without other part in bringing wellness to life. Hence, it is that amazing combination where prevention, cure and wellness of patient are taken care of.

Pharma-Nutrition in New Normal era:

Pharma is transiting from Medicines to Food for Special Dietary Use (FSDU) to Pharma Nutrition as the food has various dimensions and each country has its own food habits. It may a fully nutritionally balanced or there could be a total lack of it.

Nutrients are best available through food and how it is cooked, use of oil, fats and the spices are used. Food occupies a significant role in Health. Health domain in next normal era is likely to witness significant changes across the world.

Beyond that it is a matter of palate and organoleptic senses issue. Few May live life with burgers and aerated drinks, few may have their own ways.

However, obesity in childhood and Diabetes in younger age makes us feel that there is a need of something like Pharma – Nutrition.

 Pharma- Nutrition convergence

Father of medical practise Hippocrates has already said that “Food be thy medicine, Medicine be thy Food and walk a mile….” which is a powerful message on the medical practise all over the world. A step beyond, traditional Indian medicines, provide a three cornerstones formula for fullness of health!

  1. Ahar
  2. Vihar
  3. Aushadhi…..

Essentially Diet, Exercise and Medicines!!

Fig. 1.1: Pharma Nutrition Convergence

To effectively respond to viral infections, pharmaceutical products can repair the inflammatory and degenerative regions that degenerate in the respiratory tract and restore homeostasis of the metabolic processes. Simultaneously, nutrition and micro-nutrients continuously build up immunity of the same patient. Is it not Pharma-Nutrition has symbiotic effect to make patient healthy?

Other way round also, immuno-protection is the corner stone of the medical practise. The preservation of the immune system is the strategic measure of public health in social and clinical management of life-span extension world-wide.

Growth and opportunities for Pharma-Nutrition

A. Technology influence:

On one hand as a result of fermentation technology there are ways of creating plant products and on the other hand scientists are taking help of making the nutrients available in precise quantity as per individual need.

 One is acting at developmental stage and the other one is looking at designed quantity for the patient!

It is during the knowledge dispersal stage where cross-disciplinary excerpts carry out joint research in time. Like economy is going towards “Shared Economy”, research is also moving towards “Shared Knowledge” and insights to shorten time and makes a meaningful contribution which in turn leads to technology concurrence.

B. Human microbiome:

Pharma – Nutrition concept should aim at searching its soul in human microbiome.  More insights from human microbiomes would generate more solutions for human beings.

Fig. 1.2: Growth and opportunities for Pharma-Nutrition

C. Pharma-Nutrition ingredients:

 The fullness of health approach should be derived from the strengths of both disciplines. Strengths of pharmaceuticals industry for its R&D capabilities, defining quality, safety and efficacy as well as standards of each molecule or evidence-based nature of discerning product can be combined with nutraceutical strengths of nutrition, clinical nutrition, biochemistry, bioavailability, bio markers, to ensure wholesome heath progress. Several bioactive compounds including fibre, secondary plant molecules, friendly bacteria, essential fatty acids, probiotics and probiotics can be manufactured with promising value proposition.

Moreover, many pharma molecules are extracted from natural plants or by technology which humans can use as medicines or as nutrients. Vitamins, minerals, curative and prophylactic solutions have been derived from many such combinations.

Nutraceutical molecules like Lutein, Lycopene, Zeaxanthin, Spirulina and others have in-built properties to prevent and also cure few medical conditions.

Optimal health and elimination of chronic disease can be accomplished by this combination.

D. Combating malnutrition:

It is perceived that a number of modern diseases are linked to poor diets and the concept of “malnutrition”, even in those who are getting sufficient quantity of calories and lacking proper balance of several food ingredients such as amino acids, peptides, minerals, etc. Furthermore, there is budding evidence to indicate that definite nutritional balance through supplement can preserve patient health beyond widely used medicinal treatments.

Emerging issues

The new ‘Pharma-Nutrition’ has to face five major challenges:

  1. Education to healthcare providers
  2. Difficulty in patenting the products
  3. OTC prone nature of Nutraceutical products
  4. Prescription limitation of dieticians and nutritionists
  5. Belief system of HCPCs

Pharmaceutical companies will learn to collaborate for benefits of patient’s health. Nutrition companies need to improve their research and development to enhance their scientific capabilities as well as building key relationship with drug companies and practitioners.

New landscape

Pharma-Nutrition may not be a concept in practise as it is observed that majority of specialities have the tendency to provide nutrition benefits to patient at a particular function where they feel it’s better to provide some sort of strength to the patient.

Modern medicines usually focus on single target condition and provide entire relief or cure, irrespective of its effects on other organs. On the contrary, the multi-target medicines (Pharma-Nutrition) may be used in synchronised way to provide maximum benefit to patient.

 

References:

  1. G. Folkerts, Pharma-Nutrition-An Overview_Springer_ www.springer.com_Accessed on 5.11.2020
  2. Tamar C. Weenen, Bahar Ramezanpour, and Eric Claassen_ Food-Pharma Convergence in Medical Nutrition-best of Both worlds_PLoS One_journals.plos.org_Accessed on 5.11.2020
  3. Niki A Georgiou, Johan Grssen, Renger F Witkamp_ Pharma-Nutrition interface: the gap is narrowing_PubMed.gov_pubmed.ncib.nlm.nih.gov_Accessed on 5.11.2020
by admin admin No Comments

Maximizing Indian API Opportunities

Corona virus disaster has turned out to be an eye-opening situation because of which many powerful nations have suffered and are still suffering. Number of small and big businesses are facing adverse impacts and Pharma industry is not an exception. China is the source of 40% of the global APIs & dominating 68.3% of chemical API market worldwide. In 2018, APIs exported from China accounted for 81% ($30 billion over $37 billion) of total value of exported Chinese pharmaceutical products. Indian pharmaceutical industry despite being a global market leader at generic drug formulations, largely depends on imported APIs from China. APIs which are used to manufacture at least 12 essential drugs such as paracetamol, ranitidine, ciprofloxacin, metformin, acetylsalicylic acid, ofloxacin, metronidazole, ampicillin, amoxicillin, ascorbic acid and some fermentation-based intermediates for which India solely depends on china.

The wise steps taken by Indian government for pharma during this crisis are one of the most important growth propelling factors. The government has now come up with two schemes for pharma; one is the PLI scheme which gives some financial incentives based on sales made by selected manufacturers for 41 products which covers around 53 APIs and the incentive ranges from 5-20% based on the incremental scales. That is going to help companies in terms of bridging the gap between the Chinese prices and India price to some extent. The second scheme which the government has come up with is the bulk drug park and this scheme is primarily to provide easy access to world class common infrastructure which will be located in these parks where companies can come, set up and make use of the common infrastructure. And this is again for a period of five years. As we need to build our strength, the government has come up with these schemes which should help in compensating price gap between China and India to some extent.

India is both competitor and customer of the Chinese API industry:
We are currently the largest producers of generic medicines with a share of 20% of total global production, catering to over 60% of world’s demand. Third-largest medicine market in the Asia Pacific region with Well-established, strong local manufacturing capabilities, with an international export profile are the factors which are really highlighting our identity as ‘Pharmacy of the world’. India is by far the world’s champion of drug master files (DMFs). Drug master files (DMFs) are voluntary submissions to the import country authority, and contain confidential information about human drug products. APIs belongs to the Type II of DMFs, which is concerned with drug substance, material used in their preparation, or drug product. While China holds 12% of DMFs from the U.S., India holds almost half of them. Being the largest holder of DMSs gives India the edge to export higher-value APIs, enlarging the industry’s attractiveness. Indians generally speak better English than Chinese, which facilitates pharmaceutical trade with developed countries. Access to low cost vaccines, affordable generics & HIV treatment from India are some of the greatest success stories in Indian pharmaceutical industry. It is now widely accepted that without the likes of Sun Pharmaceutical, Ranbaxy, Dr Reddy’s Laboratories, Cipla and dozens of smaller Indian companies, many African countries would not have been able to cope with the public health challenges they face. No wonder India is called the “pharmacy to the world”.

Specialty areas to concentrate in future:
HPAPIs:
Nowadays, there is an area of interest in API domain called as HPAPI- High-potency active pharmaceutical ingredient, gaining its identity in Pharmaceutical market worldwide. They are APIs that require special handling due to toxicity and used in extremely small doses in finished drugs. Traditional examples of HPAPIs are cytotoxic compounds and sex hormones such as estrogen. Deeper analysis says that, the generic side of the industry will drive meaningful growth in the HPAPI market. Generics is one of the strongest domains in Indian pharma sector. Having said that, there exist bundles of opportunities in HPAPI sector for India. As per the latest report published by Research Dive, the global HPAPI market is estimated to generate 42,491.7 million and rise at a CAGR of 10.5% during the forecast period from 2020 to 2027. Oncology-focused medicines are one of the leading molecules creating maximum growth due to innovative pipeline candidates and upcoming generic entries. The Asia Pacific region is estimated to witness the fastest growth.
We are now emerging as a 2nd highest supplier base for generics with HPAPIs. Main API producers are headquartered in 24 different countries/territories, though most are based in either India or mainland China. New product introductions are a core growth driver for the generic API industry, and many of the upcoming opportunities are oncology-focused, high-potency compounds. Accordingly, many manufacturers across many territories have been making investments in HPAPI capabilities. Thus, companies should anticipate similarly high levels of competition as product markets develop. Looking at our nation who is blessed with ancient history of medicines and generic portfolio, profitable growth is anticipated in this area in near future. Rather than representing a well-differentiated, more insulated market segment, trends in HPAPIs are still aligned closely with the underlying dynamics of the pharmaceutical industry. Investments in this part should be viewed as essential steps to keep pace with the market.

API & data security:
Now looking into API security, the potential for insider theft exists at every level of the pharmaceutical production and distribution chain. Individuals employed at production sites, distribution centres, and pharmacies are all potential insiders. The API is stored in a secured vault until it is ready for use. It is then moved to the production area, where it is combined with inactive ingredients to make the final dosage form like pills. The pills are then packaged and sent out to distributors, leaving the control of the original facility that made them. In this whole process, there are chances that a small quantity of APIs can be lifted unofficially. Manufacturers can’t afford to overlook such malpractices as most of the APIs are highly expensive. Fortunately, at the pharmaceutical distribution sites, most employees are professionally licensed pharmacists and pharmacy technicians, bound by the ethical standards and keenly aware that a breach would result in the loss of their licenses. Quality assurance (QA) plays a central role in pharmaceutical production, and it is used as an element of theft prevention as well. At production sites, manufactured pills are pulled at random for QA checks. While these checks are primarily intended to ensure accurate formulation, they also provide a check against the diversion of API that would lead to detectable changes in pill formulation.

Way forward in API Manufacturing:
While surfing through one of the Analysis created by PwC, some of the recommendations grabbed my attension. They might not be easy to demonstrate immediately at this point but also are not unrealistic while planning for future strategies.
Some long term recommendations were:
1.Develop large clusters and provide plug-and-play infrastructural support in dedicated zones for manufacturing APIs-
• Construct 2–3 large-sized dedicated zones and lease them to private players for operating manufacturing plants.
• Set up common utilities such as solvent recovery and distillation plants, power and steam units, effluent treatment plants, common logistics centres, regulatory infrastructure and warehousing to make smaller units economically viable in these zones.
• The following support can be looked at to encourage investments in mega parks: – stamp duty waiver – 50% subsidy on water and electricity for 5 years – SGST reimbursement – 75% for 5 years – 50% subsidy on expenses incurred for quality certification/patent registration – waiver on development charges, which are currently at 9% of property cost.
• Evaluate strategic locations for these mega parks, e.g. union territories, where the centre can play a larger role in controlling costs such as like cost of land and utilities.

In the slightly longer term, the government may look at the Chinese model and work on developing clusters for API and also can fuel our HPAPI manufacturing powers. API security and surveillance technologies at industry level is also one of the major factors which has to be taken care of. An emergency is inevitable and it always affects in a very unpleasant manner if we are not fully prepared to deal with it. Self-reliance is must and we have to get habituated to it. India for India and India for global is the strategy that we need to follow. Afterall we have to give justice to ‘Make in India’.

by admin admin No Comments

Pharma mergers and acquisitions: – An initiative towards new business opportunities

Pharma mergers and acquisitions: – An initiative towards new business opportunities

The Biopharmaceutical industry is probably one of the most active sectors for mergers and acquisitions. These industries do greater number of deals and transactions than any other sector. Both merger and Acquisition are an essential component of the pharmaceutical business model and are crucial for achieving growth and competitive advantage.

How M&A is benefiting the pharmaceutical industry

The single most essential driver for changes in the Pharmaceutical industry is the ever-increasing cost of drug development, which can be controlled with the help of M&A to a greater extent. Most companies can no longer afford to carry out R&D and require high financing or Acquisition for late-stage trials to find innovative compounds and need the capability to navigate complicated regulatory pathways, which are only possible by big pharmaceutical industries. Hence, big pharmaceutical companies who want to enter a new industry or expand their business towards innovation merge with other companies or acquire smaller, creative companies by funding them or buying that company’s stakes. This is how merger and Acquisition can benefit both the big and small pharmaceutical industry.

Case Study: –

The biggest M&A (mergers and acquisitions) of 2020 are as follows: –

AstraZeneca & Alexion: –

By far, one of the biggest pharma deals of the year 2020 was between AstraZeneca and Alexion, where AstraZeneca offered a deal worth $39 billion to Alexion. Alexion has predominantly featured among the top list of biopharma takeover prospects in the last few years. With the purchase, AstraZeneca will strengthen its immunology franchise with a blockbuster of $4 billion, plus a pipeline of 11 drugs for autoimmune and rare diseases. The boards of directors of both industries have unanimously sanctioned the acquisitions. With both the sectors’ shareholders’ consent, the purchase is poised to close in Q3 2021. Upon completion, Alexion shareholders will also get a 15% stake of AstraZeneca.

Way Forward with Mergers and Acquisitions in the fiscal year 2021:

Mergers and Acquisitions, an aspect of the business world that has been rapidly growing in recent years, are poised to bloom in the year 2021 and beyond as it is one of the easy ways for pharma companies to gain horizontal or vertical integration in an industry without having to break into a new part of it from scratch. Due to the pandemic, as the market was at a complete standstill in deal activity, smaller innovative pharmaceutical companies are looking for funds and, bigger pharmaceutical industries are looking for innovations, which means that there is even more significant potential for more M&A deals to take place in the coming years as pharma businesses are recovering and are determining the best and easy way to navigate and grow the market.

REFERENCES: –

by admin admin No Comments

Revolutionizing pharmaceutical R & D sector

Revolutionizing pharmaceutical R & D sector

India has thrown a right smack on International co-operation by sending vital medicines to many countries during the pandemic, which has led India’s pharmaceutical sector to boom as a source of employment and innovation and become a global healthcare leader provider in need. With a well- equipped and low-cost skilled workforce, India is playing a significant role as a global manufacturing hub. This makes the country be on a growth trajectory. From the past few years, world-class competence, advantageous market conditions, robust framework, pecuniary and non-pecuniary incentives, and a growing R & D ecosystem have made India one of the most remunerative pharmaceutical sectors globally. India has allured tremendous praise and acknowledgment across various countries to globally recognize its on-going and practical steps to export this vital drug. 

India’s significant advantage is:

  • Funding in big-scale manufacturing pharma product units and expanding the business.
  • Improving India’s ‘soft skills’ through technical knowledge and competence building and help to other developing and developed countries.
  • strengthening the research & development ecosystem and Fuelling pharmaceutical exports
  • Enhancing access to efficacy and good secondary/tertiary health services.

According to the IPA McKinsey Report, Indian Pharmaceutical industry is poised to increase its revenue from $38-40 Bn to $120-130 Bn by 2030, with a CAGR of 11-12%.

Source :IPA Mckinsey Report 2020

Therefore, India is increasingly known as the ‘pharmacy of the world,’ or ‘pharma hub,’ exporting its pharmaceutical products globally.

Advanced technologies used in Pharma R&D: 

Nanotechnology and Microarray are the new emerging technologies in the pharmaceutical R & D sector. Along with this pharmaceutical R & D sector make use of FAIR (Findability, Accessibility, Interoperability, and Reuse), AI-enabled digital platforms, research partnerships with academia and digital tech companies, AI for drug discovery, data principle, and blockchain technology, which is becoming a new level of sharing information and transparency to reduce many challenges faced by pharmaceutical industries. These advanced technologies have developed success rates and have minimized the time and cost of drug discovery.

 Path Ahead: 

Healthcare is taking centre stage due to pandemic onset, which is likely to remain at the public’s utmost priority even in the aftermath of COVID-19 worldwide. This is a tremendous opportunity for the domestic pharmaceutical players to play a leading role in global drug management by emerging as the global ‘medical superpower’ by providing medical expertise, essential drug treatment framework, and competency building to other nations with limited prospects. 

India being the strategic industry and with the advantage of both reach and scale, it is essential to make a collaborative effort with regulatory agencies and government to help build an excellent ecosystem that will help the industry to grow by 11-12%, which will make India continue to be the ‘World Pharmacy’ and soon be the larger producer worldwide.

References: 

  1. https://www.investindia.gov.in/siru/india-pharmacy-world
  2. https://joinhubpharma.com/why-india-is-a-hub-for-pharma-manufacturing-worldwide/

 

by admin admin No Comments

Digitalisation & Pharmaceutical World

Digitalisation & Pharmaceutical World

The pharmaceutical manufacturing industry is growing drastically due to the increasing demand for its service. Digitalization can embrace almost all spheres of pharma industry, especially manufacturing. Let us see how!

Five Paradigm Shifts in Pharmaceutical industry: 

A comprehensive approach is necessary because of five fundamental shifts in how the pharmaceutical industry will be shaped in the coming years. These five paradigm shifts are as follows: 

  1. Minimizing Variations: Pharmaceutical companies can run historical data on Chemistry, Manufacturing, and Control (CMC) by building an advanced analytical model to determine the impact of individual changes. Pharmaceutical companies can use modern and new technologies to understand better how input parameters such as operator training levels, raw materials options, and machine settings will affect the quality of products and outcomes. To eliminate testing and cut throughput times in half, companies can control over input parameters to regulators. This automatically boosts efficiencies, as most of the quality control and quality assurance tasks disappear. Also, by mapping outputs to inputs, companies can proactively optimize all inputs and thus reduce variations. 
  2. Real-time data to map market trends: Internal and external indicators, big data, and machine learning algorithms can be leveraged by the industry stakeholders to forecast trends and automatically identify and mitigate risks such as quality issues, deviations, and machine failures, etc. 
  3. Digital optimization: The real-time digital twin stimulation allows companies to steer the process presciently by assuming the effect of adding a new machine, changing the team allocation, or changing schedules. This can help the company optimize production parameters for a highly complex system, proactively and accurately, without risk. Companies can also build digital stimulation of production processes on individual machines, factories, labs, or the entire manufacturing network. This is a significant advancement in efficiency compared to the traditional approach of going through historical data manually to spot trends.

    Fig 1.1 Five Data Driven Paradigm Shifts in Pharmaceutical industry

  4. Automation through robotics: Digital robots can autonomously handle supply scheduling and planning measures, using self-learning algorithms to support decisions such as corrective and preventive actions (CAPA) or portfolio margin optimization. Such tools are emerging to improve knowledge work, automation, and administrative processes. Suppose there is any deviation in a product. In that case, natural language processing can be used, which can help to show where and what went wrong and compile it into a Pareto diagram or some other type of visualization. All these solutions can reduce the company’s time by 10% but by 90-100%. 
  5. Reducing human errors: Human error is the biggest weakness in pharma production. Tasks done by humans are almost 92% accurate statistically. This does not comply with pharma expectations. Therefore, new digital systems that support operators in daily tasks highly repetitive have a massive increase in the pharma industry. These tools can let managers know if something is going wrong or is likely to go wrong.

Future prospect: Digital manufacturing in pharma is the industry’s new reality. Leading companies can develop a roadmap to implement and capture substantial gain in production capacity by 40% and reducing unit costs by 15%. The companies can embrace innovation and position themselves to compete in a future that will look very different from today.

References:

  1. https://www.epicflow.com/blog/2020-challenges-and-trends-in-pharmaceutical-industry/
  2. https://www.mckinsey.com/business-functions/operations/our-insights/how-data-is-changing-the-pharma-operations-world#

 

by admin admin No Comments

How AI Can Play a Role in Tackling the COVID-19 Pandemic?

How AI Can Play a Role in Tackling the COVID-19 Pandemic?

The global healthcare industry faced the most significant health challenge in 2020. To protect ourselves against the novel COVID-19 virus and lower the overall disruption many AI companies started to develop new tools to overcome this difficulty. Here are some keyways that prove how AI is essential in tackling COVID-19.

  • Containing the Spread:

AI can be harnessed in forecasting the spread of the virus by developing an early warning system. The one thing that AI excels in is analysing and uncovering patterns in vast data swathes. This is precisely what makes AI the perfect tool for modelling and tracking the distribution of the virus. Facebook gives an example of how this ability was utilized in practice; the AI works by sharing anonymized data about people’s movement through mapping software, which enabled Facebook to generate accurate population density estimates that offer a clear picture of when and where people were congregating. Hence, such tools are useful for tracking the virus’s spread and allocating medical resources more efficiently.

  • Diagnosing the Virus: 

First, to control the virus effectively, we need to know who has already overcome the infection, who has it, and who has never been infected. Hence, many companies tackled this challenge by launching the Coronavirus AI solution, which helps clinicians detect and monitor the virus. It even lowers the medical practitioners’ burden by allowing them to locate the virus on images of the patient’s lung, based on the data derived from the vital statistics. AI provides essential information for resource allocation by prioritizing the need for ventilators and respiratory supports in the Intensive care unit.

  • Drug Development: 

Never has mankind witnessed such a race for developing a vaccine against a pathogen or virus. Vaccine development can be a laborious and lengthy process, mainly due to the human immune system’s complexity and its variability among different groups and people. The pace of the discovery can be enhanced manifold by witnessing the power of AI. Entities have leveraged AI platforms, genomics, computing, system biology, and bioinformatics, as these technologies can anticipate where the disease will go next and identify drugs that will be effective against COVID-19.

Way Forward: 

Soon, AI will play a significant role in the pharma industry to explore the healthcare sector’s unmet medical needs. In collaboration with AI companies, many pharma companies can develop cloud-based AI platforms to accelerate their drug discovery programs. These platforms will look for patterns in data and use algorithms to make accurate predictions about the potential drug molecules based on computational structure analysis, drug target, and data from in-vivo cell line studies. Hence, it shows that AI has a massive Pharmaceutical industry application in the coming years.

 

References: 

 

 

by admin admin No Comments

Importance of Sustainability in the Corporate

Importance of Sustainability in the Corporate

COVID-19 has disrupted many business processes and few have been changed in last ten months. Now, it is time to stabilise and ensure that new systems and SOPs work for improving business. 

Stability is one of the fulcrums and essential elements for sustainability.

To sustain in this environment, 4 pronged approach is essential:

Sustainability is important tool for the corporates for managing reputation & brands. It is extremely important to incorporate sustainability in wide range of a corporate like managing the internal operations, developing regulatory strategy, marketing of products & services as well as attracting & retaining talent. The reason companies incorporates sustainability strategies is basically to maintain and improve company’s reputation, strengthening positive competitiveness, leadership’s personal interest, meeting the expectations of distributors, retailers & others & helps in aligning with the business goals.

These engaged companies do more than others to communicate the programs that involve sustainability through various engagement activities like embedding sustainability data in communication with the investors. The companies should participate in sustainability rankings and/or indexes produced by financial-index companies information provides on socially responsible investing or media or PR firms. The companies should inculcate sustainability through its CSR activities. They can also publish a sustainability section in their corporate website for their external audiences.

Therefore, companies that proactively handle sustainability are far more likely to explore and uncover opportunities for value development. Communicating better with customers and other stakeholders may be a first step in achieving awareness and enhancing the effectiveness of sustainability activities. Companies where sustainability is a top item on the agenda of their CEOs are twice as likely as those to introduce sustainability into the management strategies of their firms. This indicates that senior management who wish to enjoy the advantages of implementing sustainability into the overall policies of their businesses must play an active role in the initiative.

by admin admin No Comments

COVID-19 has changed the e-pharmacy market

Recently, two large mergers have been observed by Indian online pharmacy, which has not seen any substantial action for long due to the absence of proper regulations. 

 A majority stake in Chennai-based e-pharmacy Netmeds was picked up by Reliance Retail, while PharmEasy is integrating with Medlife. Drug distribution services on its website were also revealed by e-commerce firm Amazon. So the question is: has the Coronavirus pandemic outbreak affected the nation’s online pharmacy space? A study by The Indian Express highlighted that COVID-19 and a corresponding behavioural change in e-commerce have allowed or catalysed growth for online pharmacies, if not entirely. It affirmed, however, that the sector was still projected to rise sevenfold to $2.7 billion by 2023.

According to the study, this is partly attributed to the difficulties encountered by traditional pharmacies, giving their online equivalents more impetus. The study, citing experts, highlighted that e-pharmacies are expected to solve problems that conventional pharmacies might not be able to solve and a large-scale online pharmacy space is needed for this, which in turn requires tremendous investment or consolidation.

With over 8 lakh pharmacies and online set-ups, the pharmacy industry is fragmented in India. The study claimed that they both operate on three major business models, including the marketplace, franchise-led hybrid (offline/online) and inventory-led hybrid (offline/online).

However, because of no established regulations agreed by the government, many investments in the online space have been kept at bay until now. It should be remembered that, because e-pharmacies have not been restricted so far, brick and mortar chemists are vying for their operations. The proposed guidelines for e-pharmacies have been set in effect and are intended to describe, among other aspects, internet purchases, the definition of e-prescription and licensing for online businesses. It is also planned to propose how drugs can also be delivered, marketed, and stocked by e-pharmacies.

Therefore, E – pharmacies are bound to play a vital role in the future with the bulk of these patients who, without going to the clinic any time they need a prescription for their medications, will have a strong appetite for quick access to their therapeutics. Experts suggest that, owing to degrading environmental factors and unhealthy habits and diets of Indians, the figure is bound to show a multifold rise in coming years. With the growth of digital literacy in India, it is obvious that prospects are at their height in the e-commerce sector. In addition, the linking of brick and mortar stores with online portals could assist in the joint development of both online and offline pharmacies, thereby giving India’s healthcare sector much-needed improvement.

by admin admin No Comments

The impact of Covid-19 on API manufacturing & supply

As an industry, we continue to adapt to the global challenges faced during the COVID-19 pandemic and it is generally known that this will be felt for some time to come in the pharmaceutical industry.

Supply concerns are leading India to invest in local production:

The closure of several factories in China following the COVID-19 outbreak has been stated to have created the need for huge changes in the pharmaceutical industry. These factories make the basic raw materials and active pharmaceutical ingredients (APIs) important to providing patients with crucial medicines on a continuous basis. These closures have had a knock-on impact on global supply during such unpredictable and challenging times.

For around 70 percent of the APIs it uses in pharmaceutical manufacturing, India depends on China. China’s coronavirus pandemic could have theoretically turned the tables on India’s $39 billion drug development sector, and numerous meetings with stakeholders were held by India’s Department of Commerce and Pharmaceuticals to promote domestic API manufacturing. In response, the Indian government has set aside $1.2 billion for the pharmaceutical industry and announced the development of a production-related incentive scheme for essential drug and API manufacturing to change the country’s dependency on China’s supply of APIs.

There is tremendous growth in the Indian pharmaceutical industry and it is projected to rise from almost $34.3 billion in 2020 to more than $45 billion by 2025. As part of its’ China-plus-one’ strategy to fill supply gaps, the country is currently undergoing the development of 53 APIs. As India is a major supplier of generic medicines worldwide, these steps are primarily aimed at ensuring and sustaining the supply of medicinal drugs. India is currently projected to remain one of the world’s fastest growing economies.

Increased containment demand and sterile product transition in development

In addition, as pharmaceutical firms continue to hurry to create new medications, including the COVID-19 vaccine, manufacturers are looking at an increased need for sterile production capabilities. They also handle more highly potent active pharmaceutical ingredients (HPAPIs), a development in the industry that has been strengthened by current conditions. In line with this the global market for HPAPIs is projected to hit USD 34.8 billion by 2025, with a rise in rapid relief therapeutics expected to fuel this demand for HPAPIs in emerging countries such as India and China over the forecast period.

In the current pharmaceutical manufacturing climate, with such a rise in the use of HPAPIs and the need for sterile manufacturing expected to continue, pharmaceutical manufacturers need to achieve efficient, validated containment and sterile transfer, a challenge. It is a highly complex job to incorporate diverse technologies supplied by multiple manufacturers into contained and sterile production lines. Known validated split valve-based solutions for the development of common interfaces between different technologies can however, provide a cost-effective and scalable validated way to create a contained environment. In the months and years to come, such technologies will be crucial in preparing the industry for higher power and sterile production.

by admin admin No Comments

COVID-19 & Digital Transformation- A Catalyst for Change

COVID-19 was a wake-up call for pharma companies to assess the digital sophistication of their company and the potential to serve customised experiences to consumers. COVID-19 has intensified pre-existing developments in several ways: an expansion in the usage of clinical technologies and telemedicine; a drop in access to sales reps; an emphasis on patient experience; the pace of digital innovation through pharmaceutical companies.

These developments were brought into sharper focus by the pandemic and added a sense of urgency; but they were already, by it and wide, in motion. COVID-19 pressed the accelerator rather than applying the brakes on these movements.

It has also uncovered new ways to overhaul a static status quo and make drastic changes in fields that have not yet received similar focus: opportunities to facilitate telemedicine and a wider connected health ecosystem; a move towards a data-driven, tailored concierge approach for reps; deeper reaching simulated medical events; improved patient service services (PSPs) observing data-driven, personalized concierge approach

Although these methods may have been seen in the past in tiny pockets of activity, they are the latest developments influencing the future of the company enterprise. Now is the time for digital transformation to double. It has been thought about by the pharmaceutical industry for years, but today, it must come out of necessity, faster and more thoroughly than anybody expected or was ready for.

The COVID-19 should provide pharmaceutical manufacturers with a wake-up call to assess their own digital sophistication and willingness to represent clients who are tailored to show that they fully understand their requirements. A fair evaluation of the organization’s modern marketing sophistication and a focus of changes are required to meet the evolving demands and responsibilities of sales managers, HCPs, patients and careers.

Marketing leaders must understand how good their business is in three main drivers when making this assessment:

  • Using data to support corporate and marketing strategy
  • To build personal experience for customers
  • Technology to meet consumer requirements

The combined sophistication of data, customer experience and applied technology demonstrates new marketing readiness for an organization; measures against and prioritizes its business objectives. When viewed in this way, it becomes clear where the potential of a business stands, and a course of rapid evolution can be drawn up.

Conclusion:

Even before 2020, there were old ways of commercializing pharmaceutical products with brands of blockbusters, traditional releases, clear campaign combinations and generous budgets. The pandemic of COVID-19 has exacerbated these improvements and brought in many of them, including patient adherence, revised HCP practices and vanishing sales reps access. Although customer experience has once evaluated effect on the range of personal sales and frequency, its impact and importance are affected today. Customers – patients as well as HCPs – expect importance and need it more than ever before. Modern marketing impacts consumers who have customised interactions that reflect understanding and sensitivity to their needs.

Quick Enquiry Top

Your Name

Your Email

Your Phone Number

Your City

Name of the Organization

Select Category

Select Services

Select Services

Select Services

Additional Comments